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Federal Circuit Focuses on Burdens Of Proof in Travatan Z' Case
On March 18, 2014, a Federal Circuit panel of Judges Newman, Lourie, and Bryson issued a decision in Alcon Research Ltd., v. Barr Laboratories., Inc., No. 2012-1340. The unanimous decision, authored by Judge Lourie, affirmed the district court's finding of noninfringment, reversed the finding of invalidity, and affirmed the denial of a motion for judgment as a matter of law (JMOL) of noninfringement with respect to patents not asserted at trial.
Alcon owns several patents relating to its glaucoma and ocular hypertension drug Travatan Z'. Two of these patents cover methods of enhancing the chemical stability of prostaglandin compositions, by adding polyethoxylated castor oil (PECO patents). Barr filed an ANDA for Travatan Z' with the FDA, and Alcon initiated suit in U.S. District Court for the District of Delaware. The complaint initially referenced six patents but only the PECO patents were eventually asserted at trial. At trial, Alcon only presented accelerated stability study results performed on their developmental formulation as evidence of infringement.
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